Inbound Logistics | June 2026

THELASTMILE Logistics Outside the Box

As an estimated % of U.S. adults take appetite-suppressing GLP- medications, the supply chain effects are far-reaching—from skinnier truckloads to increased apparel returns. Get in shape for the changes ahead.

BULK UP Demand forecasting capabilities Healthy food offerings. Companies should take note of the hardest- hit sectors: processed snacks and beverages, alcohol, and rened grains. Package messaging to better appeal to weight-conscious consumers “GLP-1 friendly” labels on CPG goods Website product descriptions for apparel companies. Etailers should note if apparel sizes run oversized.

What Are GLP-1s? Drugs used to manage blood sugar levels for those with Type 2 diabetes. Now a blockbuster weight loss medication, brands include Ozempic, Mounjaro, and Wegovy.

MEASURING ITS IMPACT

~$140 billion Projected global sales of GLP-1 by 2030, up 2.6x from sales posted in 2024, according to TD Securities

14.6% The share of apparel exchanges where shoppers sized down in 2025, a gure that has increased for the past three years, according to a review of retailers by reverse-logistics service provider Narvar

At least 450,000 Food and beverage truckloads removed per year in the United States as a result of GLP-1 use, according to DAT Freight & Analytics. Some estimates run as high as 850,000 truckloads annually.

64 Inbound Logistics • June 2026

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